RA6TVqiMTt
Full identifier: https://w3id.org/np/RA6TVqiMTttbHd7HqvqQ9yABhCrfAenX7M5EfO9TAA4yo
Assigned to 2 classes:
Status

Nanopublication
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"Camaya I, Mok TY, Lund M, To J, Braidy N, Robinson MW, Santos J, O'Brien B, Donnelly S. The parasite-derived peptide FhHDM-1 activates the PI3K/Akt pathway to prevent cytokine-induced apoptosis of β-cells. J Mol Med (Berl). 2021 Nov;99(11):1605-1621. doi: 10.1007/s00109-021-02122-x."
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https://onlinelibrary.wiley.com/doi/10.1111/1753-0407.13252
1753-0407.13252
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description
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"Camaya I, Donnelly S, O'Brien B. Targeting the PI3K/Akt signaling pathway in pancreatic β-cells to enhance their survival and function: An emerging therapeutic strategy for type 1 diabetes. J Diabetes. 2022 Apr;14(4):247-260. doi: 10.1111/1753-0407.13252. "
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"Supplementary files relating the the analysis of the differential abundance of proteins and the differential expression of miRNA:mRNA in beta cells treated with FhHDM-1 under basal and apoptotic conditions.
Supplementary Table 3.1. Proteins with significantly different abundance in FhHDM-1 treated β-cells compared to untreated controls
Supplementary Table 4.1. Predicted gene targets for differentially expressed miRNAs in FhHDM-1 treated β-cells compared to untreated (Un) controls
Supplementary Table 4.2. Predicted gene targets of differentially expressed miRNAs in FhHDM-1 treated β-cells compared to untreated (Un) controls, common across all online miRNA gene target prediction tools mIRDB, DIANA and Target Scan
Supplementary Table 4.3A. List of predicted gene targets from miRNA upregulated in FhHDM-1 treated β-cells within each PANTHER DB category of molecular function and biological process (from Figure 2).
Supplementary Table 4.3B. KEGG pathway analysis of predicted gene targets from miRNA downregulated in FhHDM-1 treated β-cells compared to untreated controls
Supplementary Table 4.4. List of matched gene targets from miRNA downregulated in FhHDM-1 treated β-cells within each PANTHER DB category of molecular function and biological process (from Figure 4.5).
Supplementary Table 4.5. Differentially expressed miRNAs in FhHDM-1 treated β-cells exposed to pro-inflammatory cytokines, compared to cytokines alone
Supplementary Table 4.6. Predicted gene targets for differentially expressed miRNAs in FhHDM-1 treated β-cells exposed to pro-inflammatory cytokines compared to cytokines (CM) alone
Supplementary Table 4.7. Predicted gene targets of differentially expressed miRNAs in FhHDM-1 treated β-cells exposed to pro-inflammatory cytokines compared to cytokines (CM) alone, common across all online miRNA gene target prediction tools mIRDB, DIANA and Target Scan
Supplementary Table 4.8. KEGG pathway analysis of predicted gene targets from miRNA upregulated in FhHDM-1 treated β-cells exposed to pro-inflammatory cytokines compared to cytokines alone
Supplementary Table 4.9. KEGG pathway analysis of predicted gene targets from miRNA downregulated in FhHDM-1 treated β-cells exposed to pro-inflammatory cytokines compared to cyokines alone
Supplementary Table 4.10. Differentially expressed genes in the transcriptome of FhHDM-1 treated β-cells exposed to pro-inflammatory cytokines, compared to cytokines alone
Supplementary Table 4.11. Matched gene targets common between transcriptome and predicted gene targets of differentially expressed miRNA in FhHDM-1 treated β-cells under inflammatory conditions compared to pro-inflammatory cytokine only (CM) controls.
Supplementary Table 4.12. KEGG pathway analysis of matched genes downregulated in the transcriptome with their corresponding regulatory miRNA upregulated in FhHDM-1 β-cells exposed to pro-inflammatory cytokines compared to cytokines alone
Supplementary Table 4.13. KEGG pathway analysis of matched genes upregulated in the transcriptome with their corresponding regulatory miRNA downregulated in FhHDM-1 β-cells exposed to pro-inflammatory cytokines compared to cytokines alone
"
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identifier
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identifier
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arcp://name,uts_public_data_repo/29ff7e9014ff11eeacf4b15b8fae1d4e
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The assertion above
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This nanopublication
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sig
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this nanopublication
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sig
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Ziroli Plutschow
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This is the identifier for this whole nanopublication.
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this nanopublication
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http://purl.org/nanopub/x/RoCrateNanopub
RoCrateNanopub
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References
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