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 Article: Knowledge-based biomedical Data Science DataScience PositionPaper ScholarlyWork

https://doi.org/10.3233/DS-170001 doi:10.3233/DS-170001 http://purl.org/dc/terms/abstract has the abstract (this is a literal) "Computational manipulation of knowledge is an important, and often under-appreciated, aspect of biomedical Data Science. The first Data Science initiative from the US National Institutes of Health was entitled “Big Data to Knowledge (BD2K).” The main emphasis of the more than $200M allocated to that program has been on “Big Data;” the “Knowledge” component has largely been the implicit assumption that the work will lead to new biomedical knowledge. However, there is long-standing and highly productive work in computational knowledge representation and reasoning, and computational processing of knowledge has a role in the world of Data Science. Knowledge-based biomedical Data Science involves the design and implementation of computer systems that act as if they knew about biomedicine. There are many ways in which a computational approach might act as if it knew something: for example, it might be able to answer a natural language question about a biomedical topic, or pass an exam; it might be able to use existing biomedical knowledge to rank or evaluate hypotheses; it might explain or interpret data in light of prior knowledge, either in a Bayesian or other sort of framework. These are all examples of automated reasoning that act on computational representations of knowledge. After a brief survey of existing approaches to knowledge-based data science, this position paper argues that such research is ripe for expansion, and expanded application." .
This is the identifier for this whole nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua... This nanopublication http://purl.org/ontology/bibo/authorList has This is a local identifier minted within the nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua...#author-list this author list .
This is a local identifier minted within the nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua...#author-list This author list This relation links a sequence/list to its element at position 1. http://www.w3.org/1999/02/22-rdf-syntax-ns#_1 has at position 1 https://orcid.org/0000-0003-1455-3370 Lawrence E. Hunter .
This is the identifier for this whole nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua... This nanopublication date and time when the nanopublication was created http://purl.org/dc/terms/created was created on (this is a literal) "2025-04-24T06:15:44.650Z" .
This is the identifier for this whole nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua... This nanopublication links to the assertion template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate was created from the assertion template https://w3id.org/np/RAIDm7hi3C... RAIDm7hi3C .
This is the identifier for this whole nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua... This nanopublication links to the provenance template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromProvenanceTemplate was created from the provenance template https://w3id.org/np/RA7lSq6MuK... RA7lSq6MuK .
This is the identifier for this whole nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua... This nanopublication links to the publication info template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate was created from the publication info template https://w3id.org/np/RA0J4vUn_d... RA0J4vUn_d .
This is the identifier for this whole nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua... This nanopublication links to the publication info template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate was created from the publication info template https://w3id.org/np/RA16U9Wo30... RA16U9Wo30 .
This is the identifier for this whole nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua... This nanopublication links to the publication info template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate was created from the publication info template https://w3id.org/np/RAYrlN4s93... RAYrlN4s93 .
This is the identifier for this whole nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua... This nanopublication links to the publication info template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate was created from the publication info template https://w3id.org/np/RAjvEpLZUE... RAjvEpLZUE .
This is the identifier for this whole nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua... This nanopublication links to the publication info template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate was created from the publication info template https://w3id.org/np/RAoTD7udB2... RAoTD7udB2 .
This is the identifier for this whole nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua... This nanopublication links to the publication info template that was used to create this nanopublication https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate was created from the publication info template https://w3id.org/np/RAukAcWHRD... RAukAcWHRD .
This is the identifier for this whole nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua... This nanopublication the nanopublication consists of an introduction of the given resource http://purl.org/nanopub/x/introduces introduces https://doi.org/10.3233/DS-170001 doi:10.3233/DS-170001 .
This is a local identifier minted within the nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua.../sig sig http://purl.org/nanopub/x/hasSignatureTarget has as target This is the identifier for this whole nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua... this nanopublication .
This is a local identifier minted within the nanopublication. https://w3id.org/kpxl/ios/ds/np/RAj58UxAua.../sig sig http://purl.org/nanopub/x/hasAlgorithm has the algorithm (this is a literal) "RSA" .

Lawrence E. Hunter (author), Tobias Kuhn (creator), 24 Apr 2025, 06:15:44 UTC

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